Clinical decisions that start before conception
Monthly Master Class
Monthly Master Class
Act on Pediatric Disease Risk Before the First Symptom Appears
Chris Magryta, MD
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Why are more children developing asthma, eczema, and autism?
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From neural tube closure to myelination, nutrient timing matters during pregnancy.
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Delivery, feeding, and early antibiotic exposure help shape an infant's developing microbiome.
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Managing maternal insulin resistance is the strongest lever for reducing neurodevelopmental risk.
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Learn the preconception and pediatric decisions that shift a child's trajectory.
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CLASS OVERVIEW
Move Pediatric Care Upstream: From Pregnancy Through the First Years
Dr. Magryta distills the epigenetic, metabolic, and immunologic literature into clinical decisions you can apply in your practice.
You will learn:
- How maternal insulin resistance and nutrient insufficiency are linked to fetal brain development.
- Why findings in the first month of life point back to pregnancy.
- How to distinguish the asthma endotypes that respond to inhaled steroids from the one that often resists them.
- Why eczema in the first year of life is linked to nearly four times the odds of food allergy.
The course draws on published research and Dr. Magryta's pediatric clinical experience since 1999.
Pediatric Medical Training Starts After the Damage
Medical training teaches you to recognize pediatric disease once symptoms appear. Asthma gets inhaled steroids, eczema gets emollients, and autism gets a therapy referral.
None of that explains why these conditions are more common in children now than they were a generation ago.
Dr. Magryta argues the answer lies upstream, in pregnancy and the first years of life.
Maternal insulin resistance, nutrient insufficiency, chronic stress, dysbiosis, and toxin exposure converge on one shared pathway: chronic low-grade inflammation.
That inflammation reaches the fetus through the placenta. It shapes the infant's inflammatory set point,early microbial colonization, and barrier function long before symptoms appear.
This course focuses on the levers that remain modifiable at each stage: preconception, pregnancy, delivery, and the first months of life, including feeding and environmental exposures.
The cost of waiting shows up in children who arrive already sensitized and inflamed, on a trajectory that is harder to redirect.
None of that explains why these conditions are more common in children now than they were a generation ago.
Dr. Magryta argues the answer lies upstream, in pregnancy and the first years of life.
Maternal insulin resistance, nutrient insufficiency, chronic stress, dysbiosis, and toxin exposure converge on one shared pathway: chronic low-grade inflammation.
That inflammation reaches the fetus through the placenta. It shapes the infant's inflammatory set point,early microbial colonization, and barrier function long before symptoms appear.
This course focuses on the levers that remain modifiable at each stage: preconception, pregnancy, delivery, and the first months of life, including feeding and environmental exposures.
The cost of waiting shows up in children who arrive already sensitized and inflamed, on a trajectory that is harder to redirect.
Did You Know...
Did You Know...
Autism diagnoses increased from an estimated 1 in 5,000 children in 1970 to 1 in 31 today.
Duke data: half of the children later diagnosed with autism showed signs by 30 days of age.
Oxygen pressure in a normal placenta is 30–35 mmHg. Everest's summit is 52 mmHg.
Almost 90% of US women may lack enough B. infantis to break down milk sugars.
Animals exposed to Amish house dust developed no asthma. Those given Hutterite dust did.
Antibiotics in the first month of life: about four times the odds of food allergy.
Pediatric Health from the Womb and Beyond taught by Chris Magryta, MD
Why are we seeing more disease in children, and what changed upstream? Dr. Magryta has spent his career working backward from that question.
This course organizes his findings into a clinical framework you can apply in your practice.
It starts with evidence that early influences shape neurodevelopmental outcomes rather than fixing them from the outset.
It then explores maternal insulin resistance, nutrient sufficiency, stress, sleep, toxins, and the microbiome.
These concepts are applied to two conditions commonly seen in pediatric practice: asthma and atopic dermatitis.
You will learn to distinguish asthma endotypes, identify relevant clinical markers, and explore the interventions that reduced disease severity in his own patients. Later modules walk through real pediatric cases, including the labs he ordered and how each child responded.
Chris Magryta, MD, has practiced pediatrics since 1999. He presents the published research behind each recommendation, including early data from an obstetric nutrition project with a planned 500-pregnancy study.
This course organizes his findings into a clinical framework you can apply in your practice.
It starts with evidence that early influences shape neurodevelopmental outcomes rather than fixing them from the outset.
It then explores maternal insulin resistance, nutrient sufficiency, stress, sleep, toxins, and the microbiome.
These concepts are applied to two conditions commonly seen in pediatric practice: asthma and atopic dermatitis.
You will learn to distinguish asthma endotypes, identify relevant clinical markers, and explore the interventions that reduced disease severity in his own patients. Later modules walk through real pediatric cases, including the labs he ordered and how each child responded.
Chris Magryta, MD, has practiced pediatrics since 1999. He presents the published research behind each recommendation, including early data from an obstetric nutrition project with a planned 500-pregnancy study.
COURSE FEATURES
What Changes in Your Practice on Monday
1
Preconception Metabolic Assessment
Assess maternal insulin resistance and nutrient status before conception, the greatest modifiable lever for reducing neurodevelopmental risk.
2
Glucose Tolerance Reinterpreted
Understand why failing a one-hour glucose test but passing the three-hour test still warrants closer attention to blood sugar management.
3
Nutrient Sufficiency Versus Deficiency
Identify which maternal cofactors to assess when RDA-based benchmarks overlook insufficiencies that affect fetal brain development.
4
Early Infant Findings in Context
Recognize which findings in the first month of life appeared in children later diagnosed with autism and why they point back to pregnancy.
5
Asthma Endotype Decisions
Distinguish asthma types that respond to inhaled steroids from the one that often resists them, and adjust treatment before the next flare.
6
Eczema Beyond the Steroid Cream
Address the barrier, microbial, nutrient, and stress factors behind atopic dermatitis, with particular attention to its link to food allergy.
MEET YOUR INSTRUCTOR
Chris Magryta, MD, is a husband, father, pediatrician, writer, podcaster, and onion peeler who peels back the layers on why our species has become disease-prone. He has practiced medicine at Salisbury Pediatric Associates in Salisbury, North Carolina, for 24 years and sees each child as an incubator of change for human health.
He formed a clinically integrated network called Children First of North Carolina and guides a new, data-driven, prevention-focused Medicaid delivery model for North Carolina children. The company currently employs in-office social workers, care managers, nutritionists, and soon-to-be therapists to help children at high risk from social determinants navigate a healthier path.
His passion for changing a child's health trajectory has never been stronger, and he brings the business side of medicine together with the science of whole-child health.
Dr. Magryta completed medical school and pediatric residency at Emory University and the University of Virginia. In 2008, he received a fellowship in Integrative Medicine at the University of Arizona's Center for Integrative Medicine. He also completed deep dives into the curricula of the Institute for Functional Medicine and Cogence Immunology.
He formed a clinically integrated network called Children First of North Carolina and guides a new, data-driven, prevention-focused Medicaid delivery model for North Carolina children. The company currently employs in-office social workers, care managers, nutritionists, and soon-to-be therapists to help children at high risk from social determinants navigate a healthier path.
His passion for changing a child's health trajectory has never been stronger, and he brings the business side of medicine together with the science of whole-child health.
Dr. Magryta completed medical school and pediatric residency at Emory University and the University of Virginia. In 2008, he received a fellowship in Integrative Medicine at the University of Arizona's Center for Integrative Medicine. He also completed deep dives into the curricula of the Institute for Functional Medicine and Cogence Immunology.
COURSE CONTENT
Course Session Information
Course Session Information
SESSION 1
The Epigenetic Origins of Pediatric Disease
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Explain how maternal nutrition and toxin exposure change gene expression.
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Identify the critical windows when nutrient timing affects neural tube closure, neurogenesis, and myelination.
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Assess maternal cofactor status using markers that reveal insufficiency, not only frank deficiency.
SESSION 2
Maternal Immunometabolism and Fetal Outcomes
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Trace how insulin resistance drives the inflammation linked to preeclampsia, preterm birth, and neurodevelopmental risk.
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Interpret a passed three-hour glucose tolerance test that followed a failed one-hour result.
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Counsel patients on fructose and starch intake and why it matters.
SESSION 3
Stress, Toxins, and the Microbiome
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Evaluate how maternal sleep, chronic stress, and circadian disruption are linked to the infant's inflammatory set point.
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Review the delivery, feeding, and antibiotic decisions that shape an infant's early microbial colonization.
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Counsel patients on common pesticide and endocrine-disrupting exposures during pregnancy and lactation.
SESSION 4
Pediatric Asthma Endotypes and Drivers
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Distinguish the three asthma endotypes and explain why one of them often resists steroid therapy.
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Order and interpret the micronutrient, food sensitivity, and inflammatory markers that guide pediatric asthma care.
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Apply dietary and environmental changes that reduce flares without stopping necessary inhaled medication.
SESSION 5
Eczema, Barrier Function, and Food Allergy
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Understand how skin pH, barrier proteins, and microbial overgrowth drive atopic dermatitis in children.
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Explain the reported association between eczema in the first year of life and increased odds of later food allergy.
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Incorporate stress physiology and the itch-and-scratch sleep cycle into an eczema care plan.
SESSION 6
Integrating the Clinical Strategy
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Prioritize modifiable levers by their impact when several are relevant to a pediatric case.
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Translate preconception and prenatal findings into practical counseling that families can act on immediately.
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Recognize the shared inflammatory pathways connecting neurodevelopmental risk, asthma, eczema, and food allergy.
What's Included in the Course
What's Included in the Course
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Immediate access to the full Kharrazian Institute library, over 400 hours of clinical education
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30 days of streaming access to every course module, watched at your own pace
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Downloadable slide decks, course notes, and transcripts that stay yours permanently
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Direct content support in the clinician forums throughout the access period
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Live weekly discussion sessions with clinicians worldwide, plus members-only Zoom meetings and online forum participation during the 30 days
One payment of:
One payment of:
$399*
$399*
* One-Time Payment of $399 — Instant Access Upon Registration for 30 Days
* No ongoing subscription fees. No automatic renewals. No recurring charges.
Complete, all-inclusive access to this Master Class for 30 days,
Includes access to the full KI curriculum and participation in our members-only Zoom meetings and online forum.
Includes access to the full KI curriculum and participation in our members-only Zoom meetings and online forum.
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Immediate Full-Platform Access: The moment you register, you gain instant access to this Master Class, our community forums, and the entire Kharrazian Institute educational library (400+ hours).
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One-Time Investment: $399 ($495 value)
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Full 30-Day Master Class Access: Stream all video modules at your own pace from day one.
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Keep Course Materials for Life: Download complete slide decks, course notes, and transcripts.
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Direct Content Support: Ask questions about the material in our clinician forums during your access period.
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Live Weekly Discussions: Join our live weekly sessions with clinicians worldwide to discuss topics in real time.
* No subscription. No renewal. No recurring charge.
* Access opens when you register and lasts 30 days.
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